constants

aa_molecular_weights module-attribute

aa_molecular_weights = array([89.09, 121.15, 133.1, 147.13, 165.19, 75.07, 155.16, 131.17, 146.19, 131.17, 149.21, 132.12, 115.13, 146.15, 174.2, 105.09, 119.12, 117.15, 204.23, 181.19])

These values are for individual amino acids (from benchling), subtract h20_mass to get weight in a polymer

aa_polymer_molecular_weights module-attribute

aa_polymer_molecular_weights = array([71.0788, 103.1388, 115.0886, 129.1155, 147.1766, 57.0519, 137.1411, 113.1594, 128.1741, 113.1594, 131.1926, 114.1038, 97.1167, 128.1307, 156.1875, 87.0782, 101.1051, 99.1326, 186.2132, 163.176])

These values are for amino acids in a polypeptide. Add the weight of one water molecule to get the individual mass

instability_array module-attribute

instability_array = array([[1.0, 44.94, -7.49, 1.0, 1.0, 1.0, -7.49, 1.0, 1.0, 1.0, 1.0, 1.0, 20.26, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 20.26, 1.0, 1.0, 1.0, 33.6, 1.0, 1.0, 20.26, 33.6, 1.0, 20.26, -6.54, 1.0, 1.0, 33.6, -6.54, 24.68, 1.0], [1.0, 1.0, 1.0, 1.0, -6.54, 1.0, 1.0, 1.0, -7.49, 1.0, 1.0, 1.0, 1.0, 1.0, -6.54, 20.26, -14.03, 1.0, 1.0, 1.0], [1.0, 44.94, 20.26, 33.6, 1.0, 1.0, -6.54, 20.26, 1.0, 1.0, 1.0, 1.0, 20.26, 20.26, 1.0, 20.26, 1.0, 1.0, -14.03, 1.0], [1.0, 1.0, 13.34, 1.0, 1.0, 1.0, 1.0, 1.0, -14.03, 1.0, 1.0, 1.0, 20.26, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 33.6], [-7.49, 1.0, 1.0, -6.54, 1.0, 13.34, 1.0, -7.49, -7.49, 1.0, 1.0, -7.49, 1.0, 1.0, 1.0, 1.0, -7.49, 1.0, 13.34, -7.49], [1.0, 1.0, 1.0, 1.0, -9.37, -9.37, 1.0, 44.94, 24.68, 1.0, 1.0, 24.68, -1.88, 1.0, 1.0, 1.0, -6.54, 1.0, -1.88, 44.94], [1.0, 1.0, 1.0, 44.94, 1.0, 1.0, 13.34, 1.0, -7.49, 20.26, 1.0, 1.0, -1.88, 1.0, 1.0, 1.0, 1.0, -7.49, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0, 1.0, -7.49, 1.0, -7.49, 1.0, -7.49, 33.6, 1.0, -6.54, 24.68, 33.6, 1.0, 1.0, -7.49, 1.0, 1.0], [1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, -7.49, 1.0, 1.0, 1.0, 20.26, 33.6, 20.26, 1.0, 1.0, 1.0, 24.68, 1.0], [13.34, 1.0, 1.0, 1.0, 1.0, 1.0, 58.28, 1.0, 1.0, 1.0, -1.88, 1.0, 44.94, -6.54, -6.54, 44.94, -1.88, 1.0, 1.0, 24.68], [1.0, -1.88, 1.0, 1.0, -14.03, -14.03, 1.0, 44.94, 24.68, 1.0, 1.0, 1.0, -1.88, -6.54, 1.0, 1.0, -7.49, 1.0, -9.37, 1.0], [20.26, -6.54, -6.54, 18.38, 20.26, 1.0, 1.0, 1.0, 1.0, 1.0, -6.54, 1.0, 20.26, 20.26, -6.54, 20.26, 1.0, 20.26, -1.88, 1.0], [1.0, -6.54, 20.26, 20.26, -6.54, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 20.26, 20.26, 1.0, 44.94, 1.0, -6.54, 1.0, -6.54], [1.0, 1.0, 1.0, 1.0, 1.0, -7.49, 20.26, 1.0, 1.0, 1.0, 1.0, 13.34, 20.26, 20.26, 58.28, 44.94, 1.0, 1.0, 58.28, -6.54], [1.0, 33.6, 1.0, 20.26, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 44.94, 20.26, 20.26, 20.26, 1.0, 1.0, 1.0, 1.0], [1.0, 1.0, 1.0, 20.26, 13.34, -7.49, 1.0, 1.0, 1.0, 1.0, 1.0, -14.03, 1.0, -6.54, 1.0, 1.0, 1.0, 1.0, -14.03, 1.0], [1.0, 1.0, -14.03, 1.0, 1.0, -7.49, 1.0, 1.0, -1.88, 1.0, 1.0, 1.0, 20.26, 1.0, 1.0, 1.0, -7.49, 1.0, 1.0, -6.54], [-14.03, 1.0, 1.0, 1.0, 1.0, -9.37, 24.68, 1.0, 1.0, 13.34, 24.68, 13.34, 1.0, 1.0, 1.0, 1.0, -14.03, -7.49, 1.0, 1.0], [24.68, 1.0, 24.68, -6.54, 1.0, -7.49, 13.34, 1.0, 1.0, 1.0, 44.94, 1.0, 13.34, 1.0, -15.91, 1.0, -7.49, 1.0, -9.37, 13.34]])

Derived from Guruprasad, K., Reddy, B.V.B. and Pandit, M.W. (1990) Correlation between stability of a protein and its dipeptide composition: a novel approach for predicting in vivo stability of a protein from its primary sequence. Protein Eng. 4,155-161. Table III.